A Tale of Two Cannabinoids

By Mia Jane

THC and CBD are two buzzwords that seem to be on everyone’s lips when they have got cannabis on the brain. Being the two most well-known cannabinoids make it no surprise that these two acronyms have got everyone wondering…what’s the difference when it comes to THC vs CBD? We’ll discuss the science and hearsay around these mysterious cannabis components and delve into whether one really is that much better than the other. Look no further for your comprehensive guide to everything you want or need to know about THC vs CBD.

The plant genus cannabis contains hundreds of compounds, with a little over a hundred of the chemicals known as cannabinoids being present in varying strengths. With THC and CBD being the most prominent, you might have heard of one or the other or both. However, THC has long been associated with cannabis because of its effects on the human endocannabinoid system, creating the “high” that has made this weed so popular with many people. These mind-altering effects created by THC have also been used to vilify the plant for many years, creating a source of contention about the safety and potential for abuse by using cannabis.

THC vs CBD: The Science

THC is also known as Tetrahydrocannabinol. When ingested through smoking or vaporizing flower or cannabis oils or with eating edibles, THC will bind to the body’s CB1 and CB2 receptors in the endocannabinoid system, creating a cerebral or euphoric effect. This feeling is similar to the naturally occurring brain chemical known as anandamide and results in effects to memory, coordination, and sensory and time perception. THC will make a lot of people feel relaxed, and even a little drowsy, with a slight elation and sometimes a heightened appetite, also known as “the munchies.” This psychoactive effect is what makes being under the influence of THC generally more impairing than CBD.

THC vs CBD: The Legality

Besides making you feel some special kind of way, THC is only legal in a handful of states in the U.S. that permit medical and recreational use. That makes it not only less accessible, but less safe to consume THC because of potential for legal issues in states where laws do not permit the use of this substance.

THC is derived from cannabis which can only be legally grown in certain states. Cannabis plants are generally used for medical and recreational consumption and only the flowers, and sometimes the leaves are used. Plants qualifying as “Cannabis” are those that have any amount of THC over 0.3%. Now that we’ve covered the well-known THC, let’s get into the mysteries around CBD vs THC.

CBD is newer to the list of things to know about weed but is an enormously important compound nonetheless. CBD, also known as Cannabidiol, is known to be non-psychoactive and is found in both cannabis and hemp plants. Hemp plants are those with only 0.3% THC or less. CBD derived from hemp is legal in all 50 states to varying degrees, while CBD derived from cannabis is only legal only states with approved medical or recreational cannabis programs.


View this post on Instagram


A post shared by My 420 Tours (@my420toursdenver) on

THC vs CBD: Different Uses and Benefits

When it comes to THC vs CBD, THC despite its questionable legality has been said to aid greatly in pain relief, helping with sleep and stress disorders, as well as epilepsy and variety of other health conditions.  You can learn all about THC and how it is grown on a cannabis tour of your own.

Hemp plants are used for wellness and medicine, as well as industrial purposes. The flowers are generally higher in CBD making them prime ingredients for CBD-infused oils, edibles, capsules, and the like. Cannabidiol, also known as CBD, works in the body to fight inflammation and has been studied as an aid for a variety of mood disorders and neuropathic pain. CBD is also considered a “neuro-protectant” and is being studied for the treatment of neurological disorders like multiple sclerosis and Alzheimer’s. Hemp stalks – being more fibrous and thicker than regular cannabis plants –  are often made into things like hempcrete, batteries, or textiles.

Learning all about the wellness benefits of CBD is hands-on on one of these Cannabis Wellness tours, too.

thc vs cbd

THC vs CBD: The Psychoactive Difference

When you get down to the psychoactive effects of THC vs CBD, since CBD is non-psychoactive, it does not give the user a “high” per se. The cannabinoids, once ingested, will connect to the body’s endocannabinoid receptors but in a different way from THC. While THC likes to connect with both CB1 and CB2 receptors, CBD is partial to the CB1 receptors but does not connect in the same way as THC, so it does not have the same psychoactive effects.

THC vs CBD: The Entourage Effect

As far as absorption, when it comes to THC vs CBD, some people and scientists believe that CBD is absorbed into the body better with a little bit of THC, but the jury is still out on conclusive evidence. The CBD connects to these CB1 receptors causing the user to feel less depression, anxiety, and stress without the feelings of dysphoria associated with THC. The theory that various cannabinoids work better together Is known as “the entourage effect.”

Denver recreational dispensaries 5

THC vs CBD: Get Educated on Tour

In between the calming and pain relieving effects of THC and the anti-inflammatory powers of CBD for pain management, these two cannabinoids are not entirely different. While one causes psychoactive effects and is legal in only a few states, and the other is non-psychoactive and is legal throughout the U.S. Different as the may seem to some, when you’re comparing THC vs CBD, they do both come from different varieties of the same plant and bring up a feeling of elation and wellness that, while unique, is undeniable. You can learn all about cannabis plants, cannabinoids, their effects, uses, and even more on an in-depth cannabis growhouse tour so make sure to check one out today!

thc vs cbd infographic

Denver pot tours - greenhouse grow

Greenhouse Grow Tour

Every Tue, Wed, Thurs, and Fri 

11AM - 1:30PM

$69 Per Guest
Denver’s Best Grow Tour. Explore Euflora’s greenhouse, one of a few grows in CO that harnesses natural sunlight.
View Details

Denver pot tours - beer and weed

Buds & Beers: A Grow & Brewery Tour

Every Thu, Fri and Sat 


$89 Per Guest
A Cannabis-themed Beer Tour. Get lit like the locals on a party bus to a grow house, dispensaries, & a craft brewery.
View Details

Denver pot tours - cooking with cannabis

Custom Sushi & Joint Rolling Class

Everyday beginning at 11AM
$550 for parties of 3 people
Roll J's and Sushi. These is not a more creative and fun way to enjoy Denver than this right here!
View Details

Denver pot tours - sushi and joints

Sushi & Joint Rolling Class

Every Thu, Fri, and Sat

7PM - 9PM

$79 Per Guest
Sushi. Joints. Denver-style. Refine your joint rolling technique and learn to roll sushi. Then feast on your creations.
View Details

Marijuana Concentrates

Marijuana & Concentrates Tour

Every Friday

4PM - 6:30PM

$79 Per Person
Explore THC in its purest form. Step into the concentrates classroom and get inside the dabbing and vaping trend.
View Details

Denver pot tours - greenhouse grow

The Complete Cannabis Tour

Every Sat, Sun and Mon at 11:30AM

And now Tues from 2:30AM -4:30PM

$59 Per Guest
A Window Into Weed. Get a panoramic view of craft cannabis production, led by experts at Seed & Smith.
View Details

colorado vacation

All-Inclusive Vacation


Call to request

Starting at $1295
Three Days. 420 Everything. A three-day vacation package with all the best activities and a 420-friendly hotel stay.

View Details

Sushi Rolling Class Denver

420-Friendly Hotels

Year-Round Availability

Book your room today

From $129/night
You're Free to Consume En Suite! Simply use the tabletop vaporizer provided at check-in.
View Details

Cannabis Massage


8AM - 8PM

From $115 Per Guest
Mile High Massage Therapy. Pamper your body, mind, and soul with a soothing cannabis massage treatment.
View Details


Colorado Weed Trip

How to Use a Vape Pen

A Guide to Your Pocket Vaping Device
Read More
Colorado Weed Trip

Top 4 Denver Ghost Tours

Best Paired with a 420 Experience
Read More
Colorado Weed Trip

How to Stop Being High

Tips to Shorten Your Cannabis Experience
Read More
Colorado Weed Trip

Father-Son Trip Ideas

6 Trips with a Cannabis Twist
Read More
Colorado Weed Trip

What Does 710 Friendly Mean?

The Codeword for “Down To Dab” 
Read More
Colorado Weed Trip

Plan the Ultimate Girls Night Out

A Women’s Guide to the Mile High City
Read More

Pin It on Pinterest

Share This

Important COVID-19/Coronavirus Update

Out of an abundance of caution, we have made the decision to temporarily suspend ALL OPERATIONS. We will continue to monitor the situation closely and can not wait to resume normal operations as soon as it is safe and responsible to do so. Thank you for your patience, understanding, and support during these times.

If you are an existing customer wanting to reschedule, postpone and or cancel your reservation please complete the following form HERE.

Please note, we have limited staffing at this time and are doing our best to maintain CRITICAL business functions that will allow us to return to the work and customers we LOVE so dearly as quickly as possible. Your patience during this time is greatly appreciated.

Stay safe and take care of one another!

With love and respect,
The My 420 Tours Family